Wholesale · Cosmetic peptide
Wholesale Syn-Ake peptide
A fully synthetic cosmetic peptide — INCI Dipeptide Diaminobutyroyl Benzylamide Diacetate — working through a different receptor pathway from the SNAP-25 peptides. Manufactured to GMP standard at ≥98% HPLC purity with a batch COA included, and supplied wholesale and white label across Europe and internationally.
Overview
A third route to the same category
Syn-Ake is a trade name for Dipeptide Diaminobutyroyl Benzylamide Diacetate, a synthetic cosmetic peptide originated by Pentapharm. It was designed to mimic the structure of Waglerin-1, a peptide identified in the venom of the temple viper — but the material itself is manufactured synthetically and contains no animal-derived component.
Commercially it occupies the same expression-line space as Argireline and SNAP-8, but reaches it by a different route. Those two act on SNAP-25 within the SNARE complex; Syn-Ake acts at the nicotinic acetylcholine receptor. For brands, that difference supports a multi-pathway formulation story rather than duplicating an existing claim.
SARMs-Direct supplies wholesale Syn-Ake peptide to skincare brands, cosmetic manufacturers, ingredient distributors, formulation laboratories and private label buyers. All supply is GMP-certified with full batch documentation and a COA included.
Different receptor
Acts at the nicotinic acetylcholine receptor, not on SNAP-25.
Fully synthetic
No animal-derived material — suits vegan and cruelty-free positioning.
Water soluble
Straightforward in aqueous serums, unlike palmitoylated peptides.
It is not snake venom — and that matters commercially
Syn-Ake is frequently described online as a "snake venom peptide". That is inaccurate and, for a brand, unhelpful. The material is a synthetic peptide designed to resemble a component found in temple viper venom; it is produced by peptide synthesis and contains no venom and no animal-derived input. For brands pursuing vegan or cruelty-free certification, this is a point worth stating correctly on your own product pages — the synthetic origin is an advantage, not a caveat.
Compound specifications
Syn-Ake at a glance
| Product name | Syn-Ake (trade name) |
| INCI name | Dipeptide Diaminobutyroyl Benzylamide Diacetate |
| CAS number | 823202-99-9 |
| Compound class | Synthetic cosmetic dipeptide (diacetate salt) |
| Molecular weight | ≈507.6 g/mol (as diacetate) |
| Design basis | Structural mimic of Waglerin-1 |
| Origin | Fully synthetic — no animal-derived material |
| Purity | ≥98% (HPLC verified) |
| Appearance | White to off-white powder |
| Solubility | Water soluble |
| Storage | Cool, dry place. Protect from light and moisture. Refrigerate for long-term storage. |
Available quantities
Supply options
1g
Sample / trial
10g
Small batch
100g
Standard
1kg+
Bulk
- ✓ Powder or solution — solution simplifies dosing given the low use levels involved.
- ✓ Standard quantities from 1g to 1kg and larger bulk, with custom quotations by volume and supply frequency.
- ✓ White & private label supply for skincare brands and cosmetic manufacturers.
- ✓ Samples available for formulation trials — mention it in your enquiry.
Building a peptide range
Three routes into the expression-line category
We supply three peptides positioned around expression lines, working by two distinct receptor mechanisms. Brands building a multi-pathway story typically take one from each.
| Peptide | INCI | Acts on | Solubility |
|---|---|---|---|
| Syn-Ake | Dipeptide Diaminobutyroyl Benzylamide Diacetate | Nicotinic acetylcholine receptor | Water soluble |
| Argireline | Acetyl Hexapeptide-8 | SNAP-25 / SNARE complex | Water soluble |
| SNAP-8 | Acetyl Octapeptide-3 | SNAP-25 / SNARE complex | Water soluble |
ⓘ For collagen-support mechanisms see Matrixyl and Matrixyl 3000; for copper chemistry see GHK-Cu.
For your formulators
Formulation considerations
Working with Syn-Ake
- ● Water soluble and easy to handle. Suits aqueous serums, essences, gels and lightweight emulsions — considerably simpler than the palmitoylated peptides.
- ● Colourless. No tinting, unlike GHK-Cu.
- ● Low use levels. A pre-diluted solution removes weighing error at production scale.
- ● Add in the cool-down phase. Avoid prolonged high-temperature processing, as with peptides generally.
- ● Combines cleanly with SNAP-25 peptides. Different receptor, no known conflict — the basis of multi-pathway serum formulations.
General formulation guidance only. Use levels, stability and compatibility should be validated in your own formulation and stability testing. "Syn-Ake" is a third-party trade name; we supply the material by INCI designation. Responsibility for finished-product claims and labelling rests with the brand owner.
Formulation applications
Where Syn-Ake is used
- ✓ Anti-ageing serums targeting expression lines
- ✓ Eye creams and periorbital treatments
- ✓ Forehead and frown line products
- ✓ Multi-pathway peptide complexes
- ✓ Vegan and cruelty-free certified skincare lines
- ✓ Sheet masks and treatment ampoules
- ✓ Private label and white label skincare products
Quality & documentation
Every batch documented
- ✓ GMP-certified manufacturing
- ✓ ISO quality management system
- ✓ HACCP-compliant production controls
- ✓ Independent third-party HPLC testing
- ✓ Certificate of Analysis (COA) issued per batch
- ✓ MSDS available on request
- ✓ Full batch and lot traceability records
Who orders wholesale Syn-Ake
Built for cosmetic B2B buyers
Skincare brands
Expression-line and multi-pathway product formulation.
Vegan & cruelty-free brands
Synthetic origin suits certification requirements.
Private label companies
White label peptide skincare ranges.
Cosmetic manufacturers
Ingredient supply for production runs.
Ingredient distributors
Regional distribution of cosmetic peptides.
Formulation laboratories
R&D and prototype development.
Request a wholesale Syn-Ake quote
Tell us whether you need powder or solution, your target quantity, and any other peptides you're sourcing. We'll reply within 24 hours with pricing and a current batch COA on request.
COAs, bulk pricing and private label options available on request — WhatsApp +44 7880 485232 or email info@sarms-direct.com
Syn-Ake FAQs
Frequently asked questions
Is Syn-Ake made from snake venom?
What is the INCI name and CAS number?
How does it differ from Argireline and SNAP-8?
Is it water soluble?
What quantities is wholesale Syn-Ake available in?
Do you offer white label Syn-Ake supply?
Related cosmetic peptides
Buyers of Syn-Ake also order
Argireline →
Acetyl Hexapeptide-8 — the expression-line category benchmark.
SNAP-8 →
Acetyl Octapeptide-3 — premium expression-line analogue.
GHK-Cu →
Copper Tripeptide-1 — the benchmark copper peptide.
Matrixyl →
Palmitoyl Pentapeptide-4 — matrikine collagen support.
Supplied for cosmetic formulation and laboratory research purposes. Not for human consumption. Buyers are responsible for ensuring finished products comply with applicable cosmetics regulations in their market.
