Wholesale · Cosmetic peptide
Wholesale Argireline (Acetyl Hexapeptide-8)
The most widely used expression-line peptide in cosmetic formulation, manufactured to GMP standard at ≥98% HPLC purity with a batch COA included. Supplied wholesale and white label — as powder or aqueous solution — to skincare brands, cosmetic manufacturers and formulation laboratories across Europe and internationally.
Overview
The category-defining expression-line peptide
Argireline is the trade name for Acetyl Hexapeptide-8 — a synthetic six amino acid cosmetic peptide originated by Lipotec, and the compound that effectively created the expression-line peptide category. It remains the most widely formulated peptide of its type and carries strong recognition with both formulators and end consumers.
Its sequence corresponds to the N-terminal end of SNAP-25, a protein involved in neurotransmitter release at the neuromuscular junction. This is the same target as SNAP-8, which is the extended eight amino acid analogue developed after it.
SARMs-Direct supplies wholesale Argireline as powder or aqueous solution to skincare brands, cosmetic manufacturers, ingredient distributors, formulation laboratories and private label buyers. All supply is GMP-certified with full batch documentation and a COA included.
Category benchmark
The most widely formulated expression-line peptide in the market.
Consumer recognition
One of the few peptide names consumers actively search by.
Two formats
Supplied as powder or as a ready-to-dose aqueous solution.
Compound specifications
Argireline at a glance
| Product name | Argireline (trade name) |
| INCI name | Acetyl Hexapeptide-8 |
| Former INCI | Acetyl Hexapeptide-3 (still widely used) |
| CAS number | 616204-22-9 |
| Compound class | Synthetic cosmetic peptide (hexapeptide) |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂ |
| Molecular formula | C₃₄H₆₀N₁₄O₁₂S |
| Molecular weight | ≈888.99 g/mol |
| Purity | ≥98% (HPLC verified) |
| Appearance | White to off-white powder |
| Solubility | Water soluble |
| Storage | Cool, dry place. Protect from light and moisture. Refrigerate for long-term storage. |
Available quantities
Supply options
1g
Sample / trial
10g
Small batch
100g
Standard
1kg+
Bulk
- ✓ Powder or aqueous solution — specify which you need. Solution concentration to your requirement.
- ✓ Standard quantities from 1g to 1kg and larger bulk, with custom quotations by volume and supply frequency.
- ✓ White & private label supply for skincare brands and cosmetic manufacturers.
- ✓ Samples available for formulation trials — mention it in your enquiry.
Choosing between them
Argireline or SNAP-8?
We supply both. They target the same protein, and the right choice usually comes down to positioning and cost rather than one being simply better.
| Argireline | SNAP-8 | |
|---|---|---|
| INCI | Acetyl Hexapeptide-8 | Acetyl Octapeptide-3 |
| Length | 6 amino acids | 8 amino acids |
| Target | SNAP-25 (N-terminal) | SNAP-25 (N-terminal) |
| Market position | Category benchmark, high consumer recognition | Newer analogue, premium positioning |
| Typical use | Broad range, mass to prestige | Premium and efficacy-led lines |
| Page | This page | See SNAP-8 → |
ⓘ Many brands formulate both together in multi-peptide complexes. We can quote them on a single order.
For your formulators
Formulation considerations
Working with Argireline
- ● Water soluble and straightforward. It suits aqueous serums, essences, gels and lightweight emulsions, and is considerably easier to formulate with than copper peptides.
- ● Colourless. Unlike GHK-Cu it will not tint your base — useful when you want a clear or white finished product.
- ● Powder or solution. Powder gives you control over concentration; a ready-made aqueous solution simplifies dosing on the production line. Tell us which suits your process.
- ● Add in the cool-down phase. As with most peptides, avoid prolonged exposure to high processing temperatures.
- ● Pairs well in multi-peptide complexes. Commonly formulated alongside SNAP-8, Matrixyl-type peptides and copper peptides in booster serums.
A note on marketing claims
Argireline is frequently marketed with comparisons to injectable procedures. In most jurisdictions — including the UK and EU — that framing risks presenting a cosmetic as having a medicinal or device-like action, which is a regulated claim and a common cause of advertising complaints. We supply the ingredient with accurate technical documentation and would encourage you to keep finished-product claims within cosmetic boundaries, focused on appearance and skin feel. Responsibility for finished-product claims rests with the brand owner.
Formulation applications
Where Argireline is used
- ✓ Anti-ageing facial serums targeting expression lines
- ✓ Eye creams for periorbital lines
- ✓ Forehead and frown line treatments
- ✓ Peptide moisturisers across mass and prestige tiers
- ✓ Multi-peptide complexes and booster serums
- ✓ Sheet masks and treatment ampoules
- ✓ Private label and white label skincare products
Quality & documentation
Every batch documented
- ✓ GMP-certified manufacturing
- ✓ ISO quality management system
- ✓ HACCP-compliant production controls
- ✓ Independent third-party HPLC testing
- ✓ Certificate of Analysis (COA) issued per batch
- ✓ MSDS available on request
- ✓ Full batch and lot traceability records
Who orders wholesale Argireline
Built for cosmetic B2B buyers
Skincare brands
Expression-line and anti-ageing product formulation.
Private label companies
White label peptide skincare ranges.
Cosmetic manufacturers
Ingredient supply for production runs.
Ingredient distributors
Regional distribution of cosmetic peptides.
Formulation laboratories
R&D and prototype development.
E-commerce beauty brands
Direct-to-consumer peptide skincare.
Request a wholesale Argireline quote
Tell us whether you need powder or solution, your target quantity, and whether you need white label. We'll reply within 24 hours with pricing and a current batch COA on request.
COAs, bulk pricing and private label options available on request — WhatsApp +44 7880 485232 or email info@sarms-direct.com
Argireline FAQs
Frequently asked questions
What is Argireline?
Is Acetyl Hexapeptide-8 the same as Acetyl Hexapeptide-3?
What is the CAS number for Argireline?
What is the difference between Argireline and SNAP-8?
Do you supply Argireline as a solution or powder?
Do you offer white label Argireline supply?
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Supplied for cosmetic formulation and laboratory research purposes. Not for human consumption. Buyers are responsible for ensuring finished products comply with applicable cosmetics regulations in their market.
