Wholesale SNAP-8 (Acetyl Octapeptide-3)

SNAP-8 (Acetyl Octapeptide-3) is a high-performance cosmetic peptide widely used in premium anti-ageing skincare formulations. Composed of eight amino acids, it is designed to target expression lines and dynamic wrinkles by mimicking the N-terminal end of SNAP-25 — a protein involved in neuromuscular signalling. It is one of the most in-demand peptide ingredients in the professional skincare and cosmeceutical market.

SARMs-Direct supplies wholesale SNAP-8 to skincare brands, cosmetic manufacturers, ingredient distributors, formulation laboratories and private label buyers across Europe and internationally. All supply is GMP-certified with full batch documentation and a COA included.

SNAP-8 was developed as an extended analogue of Argireline (Acetyl Hexapeptide-3), one of the most commercially successful cosmetic peptides. Both compounds target SNAP-25 — a key protein in the SNARE complex involved in the release of neurotransmitters at the neuromuscular junction. By competing with SNAP-25 for a position in the SNARE complex, SNAP-8 is proposed to modulate the signalling cascade that leads to muscle contraction, reducing the formation and deepening of expression lines.

As an eight amino acid peptide versus Argireline's six, SNAP-8 is generally considered to have a stronger activity profile at equivalent concentrations, making it a preferred choice for premium anti-ageing formulations where efficacy positioning is important for brand differentiation.

It is water soluble and stable across a wide pH range, making it straightforward to incorporate into aqueous formulations including serums, eye creams and moisturisers.