Wholesale · Research use only
Wholesale Cardarine (GW-501516)
A PPARδ receptor agonist — not a SARM — supplied in bulk powder and capsule formats for laboratory research. Manufactured to GMP standard at ≥98% purity, verified by HPLC and LC-MS, with a Certificate of Analysis on every batch. Strictly B2B, research use only. Please read the safety and regulatory notes below before ordering.
Overview
A PPARδ agonist — not a SARM
Cardarine (GW-501516) is a synthetic agonist of the peroxisome proliferator-activated receptor delta (PPARδ). It has no activity at the androgen receptor, which means it is not a SARM despite being routinely grouped with them by suppliers and search engines. It was developed jointly by GlaxoSmithKline and Ligand Pharmaceuticals, and was investigated for dyslipidaemia and metabolic syndrome before development was discontinued.
SARMs-Direct supplies wholesale Cardarine in raw powder and encapsulated formats to research institutions, laboratories and qualified B2B distributors. All supply is strictly B2B and sold for laboratory research purposes only. Given this compound's development history and regulatory status, we ask buyers to read the notes below.
Different receptor
PPARδ agonist — no androgen receptor activity at all.
Development halted
Discontinued in 2007 following preclinical toxicology findings.
WADA prohibited
Banned in sport under the metabolic modulators category.
Compound specifications
Cardarine at a glance
| Compound name | Cardarine |
| Common aliases | GW-501516, GW1516, Endurobol |
| CAS number | 317318-70-0 |
| Molecular formula | C₂₁H₁₈F₃NO₃S₂ |
| Molecular weight | 453.5 g/mol |
| Compound class | PPARδ (PPAR-delta) receptor agonist |
| Originators | GlaxoSmithKline / Ligand Pharmaceuticals |
| Development status | Discontinued (2007) |
| Purity | ≥98% (HPLC & LC-MS verified) |
| Appearance | White to off-white crystalline powder |
| Storage | Cool, dry place. Protect from light and moisture. Stable at room temperature when sealed. |
Important
Safety & regulatory status
We state this openly because professional buyers evaluating this compound need an accurate picture, and because it directly affects how it can lawfully be supplied and used.
Development discontinued following toxicology findings
Development of GW-501516 was halted in 2007. Long-duration rodent carcinogenicity studies conducted at high doses reported tumour development across multiple organ systems, and the programme was not taken forward. No clinical development has resumed since.
Prohibited in sport. Cardarine is listed by the World Anti-Doping Agency as a prohibited substance under the metabolic modulators category, and WADA has previously issued a direct public warning to athletes regarding its use.
Supplied for laboratory research only. This compound is not approved for human consumption by any regulatory authority, is not a dietary supplement ingredient, and must not be sold or represented for human use. Buyers are responsible for ensuring their intended use and onward supply comply with the regulations of their jurisdiction.
Available formats & MOQs
Supply options
FORMAT 01
Raw powder
MOQ 10g per batch
Available in 10g, 50g, 100g, 500g and 1kg quantities. Vacuum-sealed in double-layered pouches with no compound names on outer labels. COA included. See raw powders →
FORMAT 02
Encapsulated
MOQ 1,000 units per strength
Capsule strengths produced to your specification, supplied in tamper-evident bottles with research-use labelling. See capsules →
FORMAT 03
Liquid suspension
MOQ on request
Available on request. Contact us for concentration options and minimum order quantities for your requirement.
Given its regulatory status, Cardarine is supplied with Research Use Only labelling as standard and is not offered as a consumer-facing white label product.
Research context
Mechanism & development history
PPARδ is a nuclear receptor involved in the regulation of lipid metabolism and substrate utilisation. Agonists of this receptor alter the transcription of genes governing how tissues metabolise fatty acids and glucose, which is why the pathway attracted pharmaceutical interest for dyslipidaemia and metabolic syndrome.
GW-501516 was developed as a selective PPARδ agonist by GlaxoSmithKline in collaboration with Ligand Pharmaceuticals, and progressed through early clinical evaluation for lipid disorders. Preclinical work also examined its effects on endurance and substrate utilisation in animal models, which is the origin of the "Endurobol" nickname and much of its subsequent notoriety.
Development was discontinued in 2007 after long-duration rodent studies at high doses reported carcinogenic findings. The compound remains available as a research chemical and continues to appear in academic literature on PPARδ signalling, but there is no active clinical development programme and no approved human application.
Quality & documentation
Every batch documented
- ✓ GMP-certified manufacturing
- ✓ ISO quality management system
- ✓ HACCP-compliant production controls
- ✓ Independent third-party testing — HPLC, LC-MS, ICP-MS
- ✓ Certificate of Analysis (COA) issued per batch
- ✓ MSDS available on request
- ✓ Research Use Only labelling as standard
- ✓ Full export documentation provided
Who orders wholesale Cardarine
B2B buyers we supply
Research institutions
PPARδ signalling and lipid metabolism studies.
Contract research organisations
Reference and comparator compound supply.
Analytical laboratories
Reference standards for detection and screening method development.
Qualified B2B distributors
Research chemical distribution under RUO terms.
Request a wholesale Cardarine quote
Tell us the format and quantity you need, along with your research context. We reply within 24 hours with pricing and a current batch COA on request. B2B research enquiries only.
COAs and batch documentation on request — WhatsApp +44 7880 485232 or email info@sarms-direct.com
Cardarine FAQs
Frequently asked questions
Is Cardarine a SARM?
Why was Cardarine development discontinued?
Is Cardarine banned in sport?
What is the CAS number for Cardarine?
What purity is your wholesale Cardarine?
Can Cardarine be supplied as a consumer product?
Related compounds
Other compounds in our range
Ostarine (MK-2866) →
The most widely studied SARM, with the most extensive clinical trial record.
Ligandrol (LGD-4033) →
Strong receptor binding affinity at lower concentrations.
RAD-140 (Testolone) →
High receptor selectivity, widely researched non-steroidal SARM.
MK-677 (Ibutamoren) →
Growth hormone secretagogue with oral bioavailability.
All products are sold strictly for laboratory research purposes and are not for human consumption. Buyers are responsible for ensuring compliance with applicable regulations in their jurisdiction.
