Wholesale Andarine (S-4)

Andarine, commonly designated S-4, is a non-steroidal selective androgen receptor modulator developed by GTx Inc. — the same originator as Ostarine (MK-2866). It was among the first compounds of its class to be investigated, with research programmes examining benign prostatic hyperplasia, muscle wasting and osteoporosis. It remains widely referenced in the SARM literature as an early reference compound for the class.

SARMs-Direct supplies wholesale Andarine in raw powder and encapsulated formats to research institutions, supplement brands, white label operators and distributors across Europe and internationally. All supply is strictly B2B and sold for research purposes only.

Andarine was developed by GTx Inc. as a non-steroidal androgen receptor agonist with tissue-selective activity, and was among the earliest compounds to establish the SARM class. Research programmes examined applications in benign prostatic hyperplasia, muscle wasting and osteoporosis. It has a comparatively short half-life relative to later compounds such as Ligandrol and RAD-140, and did not progress to late-stage clinical development.

A documented characteristic worth knowing: the Andarine literature consistently reports transient visual effects — a yellow tint to vision and delayed adaptation to darkness — attributed to interaction with binding sites in the retina. The effect is reported as dose-related and reversible on discontinuation. We mention it because it is the single most-documented characteristic of this compound and buyers evaluating it for research programmes should have an accurate picture.

Andarine is frequently used as a reference compound in analytical work, including the development of detection and screening methods, given its early position in the class and well-characterised profile.